Hepatosplenic T-cell lymphoma appearing in the peripheral blood
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منابع مشابه
Hepatosplenic T-cell lymphoma appearing in the peripheral blood.
A previously healthy 23-year-old Japanese male had complained of a fever lasting a month. A physical examination revealed marked hepatosplenomegaly without significant peripheral lymphadenopathies. Routine laboratory tests showed a hemoglobin level of 9.1 g/dL, 95 3 10/L platelets, 7.1 3 10/L leukocytes, and an elevated lactate dehydrogenase level of 522 U/L (reference interval, 120-220 U/L). A...
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متن کاملHepatosplenic T-cell lymphoma: A case series.
Hepatosplenic T-cell lymphoma (HSTCL) is a rare type of Non-Hodgkin Lymphoma (NHL), grouped under the mature or peripheral T-cell lymphomas. It is characterised by extranodal infiltration and proliferation of malignant T-cells within the sinusoids of the liver, sinuses and red pulp of the spleen, and the bone marrow. The tumour cells express CD2 and CD3, but are CD4, CD5 and CD8 negative and ex...
متن کاملLiterature Review : Hepatosplenic T - cell Lymphoma
Hepatosplenic T-cell lymphoma (HSTCL) is a rare type of T-cell lymphoma with poor clinical outcomes. Typical clinical features include a predominance of young male with fever, hepatosplenomegaly and cytopenia with the absence of appreciable lymphadenopathy. Diagnosis is based on examination of peripheral blood and histopathology of bone marrow, spleen or liver. In addition, immunophenotyping an...
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ژورنال
عنوان ژورنال: Blood
سال: 2013
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood-2013-01-478404